Boosting antibody-dependant cellular cytotoxicity against tumor cells with a CD137 stimulatory antibody
نویسندگان
چکیده
Monoclonal antibodies (mAb) induce tumor regression through antibody-dependant cellular cytotoxicity (ADCC). We recently showed that an agonistic anti-CD137 mAb stimulates natural killer (NK) cells which have been activated by a tumor-specific mAb, resulting in increased ADCC against cancer cells.
منابع مشابه
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